Research Poster Winner
Research Day at the Oklahoma Capitol
Manal Gasem, junior chemical engineering
student from OSU, was one of 4 OSU students selected to present her
research results at the State Capitol as part of a week that
showcased the importance of research to Oklahoma. In all, there
were 24 undergraduates representing the State’s research
universities. Manal placed 4th in the judging.
Ms. Gasem started her research as part of a
Lew Wentz Foundation grant. She writes,“After being awarded the
Wentz Research Project, I was given the opportunity to present my
research in a scientific poster competition at the state capital.
My research with Dr. Sundar Madihally, is based on the reaction our
bodies have after a severe burn trauma. It is believed that after
such an injury, the interleukin-18 (IL-18) molecule may be released
into the body. This eventually leads to the production of the
interferon-gamma (IFN-γ) molecule. The release of IFN-γ into the
body, in turn, causes many disruptions and health hazards,
including, muscle wasting, immune dysfunction, and possibly severe
infections, which are the leading cause of death in burn injury
patients. Based on stained skin samples and the quantification of
IL-18 by the creation of an enzyme-linked immunosorbent assay, there
is evidence to show that the IL-18 molecule is released into the
body after a severe burn trauma. If this is the case, a burn injury
therapy may be developed with the use of tissue engineering to block
the activity of IL-18 so all the unnecessary deaths no longer occur.
“
Congratulations to both Sundar and Manal!